Endocrine Abstracts

Introduction: Graves’ hyperthyroidism is an autoimmune disease sustained by autoantibodies binding to and activating the TSH receptor located on the thyroid follicular cell. The objective of study was to determine the presence of anti-receptor TSH antibodies for the diagnosis of Grave’s diseases and the following up after surgery, iodine and treatment with antithyroid drug.Results: In years 2006–2010 in our clinic in 265 patients for thyro...

Background: Diabetes mellitus (DM) is a common metabolic disorder and is associated with development of chronic macrovascular complications leading to significant morbidity and mortality. The aim of the study was to evaluate the prevalence and clinical profile of macrovascular complications in diabetic patients in Korca, Albania.Material and methods: A total of 456 cases with type 2 DM attending Department of Endocrine (outpatient/inpatient), from Januar...

Background: Fahr’s Syndrome, also known as striopallidodentate calcinosis is a rare form of neurological disorder characterized by abnormal calcified deposits in basal ganglia, cerebellar and cerebral cortex. Its prevalence goes from 2 to 12.5%. Etiology of this disorder is very wide and involves endocrinopathy, mitochondrial myopathies dermatological abnormalities, infectious disease or may be idiopathic. We present a case of a patient with diffuse brain calcifications d...

Background: Nephrocalcinosis is characterized by the deposition of calcium products in kidney parenchyma and tubules. It may cause acute or chronic kidney injury or be incidentally detected radiographically in a patient with normal kidney function. Most patients with nephrocalcinosis do not progress to end-stage kidney disease, but with certain underlying conditions, may be associated with progressive kidney dysfunction.Methods: The patient was diagnosed...

Introduction: Occult papillary carcinomas are small thyroid carcinomas (<1 cm) diagnosed after an initial manifestation of lymph nodes or distant metastasis. We report two cases of patients with this pattern of clinical presentation.Case description: The first case is a 21-year-old woman, with a one-year history of a growing cervical cyst. Fine needle aspiration of the cyst showed metastasis from papillary thyroid cancer. She had no previous history ...

Aim: To see the difference between salivary cortisol values and correlation with the work stress.Methods: The salivary and serum cortisol values were analysed in two groups of nurses, six nurses in the Emergency Department and six nurses in the Pathology Department at our hospital, three females and three males for each group. The samples were taken before beginning the work and after finishing the work. The cases respected all the rules for salivary tes...

Introduction: Graves’ hyperthyroidism is an autoimmune disease sustained by auto antibodies binding to and activating the TSH receptor located on the thyroid follicular cell. The diagnosis of Graves’ hyperthyroidism is based upon clinical symptoms, signs and laboratory tests confirming the presence of thyrotoxicosis, positive thyroid peroxidase (TPO) and less commonly thyroglobulin (Tg) antibodies, and finally, positive serum TSH receptor antibodies (TRab). Recently ...

Introduction: Insulinoma is a rare tumor, with peak incidence at 30 -60 years of age and more frequent in women. It is associated with a myriad of clinical manifestations: from clearly defined adrenergic and neuroglycopenic symptoms to asymptomatic hypoglycemia. We present the case of a 20-year-old patient with pancreatic insulinoma, which was surgically resected only after her second hospitalization due to repeated negative imaging.Case presentation: A ...

Introduction: Graves’ disease is an autoimmune disease that leads to a generalized over activity of the entire thyroid gland (hyperthyroidism). It is caused by TRAb thyrotropin receptor antibodies (TRAb), which bind to receptors on the surface of thyroid cells and stimulate those cells to overproduce and release thyroid hormones. Subacute thyroiditis is presumed to be caused by a viral infection or a postviral inflammatory process. It is a self-l...

Acromegaly is a rare disorder with a high morbidity and mortality rate. The diagnosis is typically prolonged over time due to a slow and hidden development of the disease. Current medical therapy for the treatment of acromegaly involves the administration of somatostatin analogues that effectively suppress excess hormone secretion. The objective of this study was to investigate the efficacy of octreotide therapy in acromegalic. A total of 32 patients have been treated with Oct...